MOTS C 40MG

Product information

Mitochondrial signaling

MOTS-c is a mitochondrial-genome-encoded peptide studied as a signal between mitochondria and the rest of the cell. The page describes folate-pathway changes, AICAR accumulation and AMPK activation, plus movement into the nucleus during metabolic stress and changes in stress-response gene expression.

Cited cell and mouse studies address glucose handling, fat metabolism, muscle function, exercise-related responses and aging-associated measurements. Population associations and studies of CB4211, a modified analogue, do not establish effects of native MOTS-c administration in humans. The page states that native MOTS-c lacks human administration trials and regulatory approval, and that long-term effects remain unknown.

For laboratory handling, it highlights oxidation-sensitive residues and recommends keeping material sealed, cold and protected from light and air exposure.

Specifications